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The purpose of this study is to test the safety of genetically changed T cells and find out what effects, if any, they have in subjects with lung cancer.Subjects will be seen frequently by the Study Physician right after receiving their T cells back.Update Star includes support for many languages such as English, German, French, Italian, Hungarian, Russian and many more.You can choose your language settings from within the program.Simply double-click the downloaded file to install it.Update Star Free and Update Star Premium come with the same installer.

Update Star has been tested to meet all of the technical requirements to be compatible with Windows 10, 8.1, Windows 8, Windows 7, Windows Vista, Windows Server 2003, 2008, and Windows XP, 32 bit and 64 bit editions.This is a single-arm study of genetically engineered NY-ESO-1ᶜ²⁵⁹T cells in HLA-A*0201, HLA-A*0205 and/or HLA-A*0206 positive subjects with advanced (Stage IIIb or IV) NSCLC.Subjects with measurable disease will be screened for general health, performance status and disease stage.Subjects will visit the clinic for safety and efficacy assessments daily from T cell infusion (Day 1) through Day 5, Days 8, 10, 12, and then weekly until week 6 and then at 8, 10, 12, 16, 20 and 24 weeks, and every 3 months until 2 years and then every 6 months until progression of their disease (or withdrawal of consent for the interventional portion of the study) Subjects who have a confirmed response (or have stable disease for 4 months) but subsequent disease progression following the initial infusion and whose tumor continues to express the appropriate antigen target may be eligible for a second infusion.All subjects, completing or withdrawing from the interventional portion of the study, will enter a 15-year long-term follow-up phase for observation of delayed adverse events.